Keywords
periodontal health
bone regeneration
cholesterol management
retrospective study
How to Cite
Abstract
Introduction: Statins, primarily used for cholesterol management, have shown potential in improving periodontal health due to their anti-inflammatory and bone-regenerative properties.
Methods: A retrospective study was conducted on 30 patients under statin medication. A control group of 30 non-statin users was selected using propensity score matching (PSM) to minimize bias. Data on pocket depth, attachment loss, and radiographic bone loss were collected at two time points: T0 and T1. Statistical analysis was performed using RStudio, with a significance threshold set at p < 0.05.
Results: The study revealed significant decrease in pocket depth (p = 0.0027), attachment loss (p < 0.001), and radiographic bone loss (p < 0.001) in the statin group compared to the control group from T0 to T1.
Conclusions: These findings suggest that systemic statins contribute to improved periodontal health. Further research is needed to confirm these effects and evaluate long-term clinical implications.