Bone regeneration using deproteinized bovine bone mineral (DBBM) in a crestal sinus elevation technique: a histological and histomorphometrical pilot study

Abstract

The aim of this study is to evaluate the percentage of new bone formation (NBF) and residual bone substitute following the use of a bovine demineralized xenograft (DBBM) in a sinus floor crestal approach elevation technique.

Materials and methods: Nine patients with unilateral or bilateral edentulous sites with less than 2 mm residual bone height under the sinus, were included in this study. Future site development was performed using deproteinized bovine bone mineral (DBBM) as graft material. In the second stage, performed after 6 to 9 months, nine implants were placed after harvesting bone biopsies from the regenerated sites. Histological and histomorphometric analysis were then undertaken to assess the regenerated bone.

Results: All the implants were placed successfully after 6 to 9 months following sinus floor elevation technique for future site development without any complications. The average percentage of new bone formation and residual bone substitute were of 24.37 % ± 13.12 % and 5.87 % ± 8.38 %, respectively.

Conclusion: Within the validity of this crestal approach in the treatment of the subantral region presenting 2 mm or less residual bone height, the DBBM has proved to be a osteoconductive biomaterials in bone regeneration procedures.